CFV4L, Piper’s Angels Foundation, CF Physio Inc., Frederico Gomez Children’s Hospital, and University of West Georgia have collaborated to research the impacts of social determinants of health deficits on a population of 79 children and young adult (average life expectancy 23 years) patients. Additionally, this project will evaluate the impact of providing basic evidenced based CF care in the form of macro and micro nutritional supplementation as well as airway clearance support to improve clinical markers, quality of life, and reduce acute inpatient utilization by mitigating the frequency and acuity of pulmonary exacerbations.